News



March 2021

New study published on clonal hematopoiesis - big congrats to Katharina

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Jan 2021

Lena successfully defended her thesis - congrats Dr. Dorsheimer

Nov 2020

Alec Gessner joint the team as PhD student - welcome Alec!

July 2020

New positions available in the lab!

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June 2020

Fighting COVID19 - support by Goethe Corona Fonds

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April 2020

Joining the BD MultiOmics Alliance

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March 2020

New PhD Student positions available!

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Jan 2020

New Review on Clonal Hematopoiesis (CHIP) published

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Dec 2019

Frankfurt University highlights our latest research

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Nov 2019

Lena published bone marrow alterations in CHIP carriers - congrats!

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Oct 2019

Editorial on NATURE paper about stem cell expansion by Michael

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Oct 2019

Ilaria successfully defended her thesis - congrats Dr. Lunger

Oct 2019

Rene received MD stipent from the Jackstädt-Stiftung at the DGHO - congrats!

Sept 2019

Our CHIP Team scored again - EHJ publication!

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May 2019

Christina´s paper about CHIP after autoSCT published in Cell Reports - congrats!

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Jan 2019

New lab positions available (PhD, Postdoc, TA)

Dec 2018

Clonal hematopoiesis contribute to ischemic heart failure - published in JAMA Cardiology

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Dec 2018

New TA position available

Dec 2018

New Postdoc position available

Nov 2018

Public Report about Rieger Lab

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Sept 2018

Excellence Cluster Cardio-Pulmonary-Institute funded!

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Aug 2018

Michael invited speaker at ISEH 2018 in Los Angeles

June 2018

New PostDoc position available

Feb 2018

MiRNA-193b in AML - great story published in JCO

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Dec 2017

Bartosch successfully defended his thesis - congrats Dr. Wojcik

Dec 2017

Bartosch and Fabian published Perspective Article in ONCOTARGET

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Basic Mechanisms in Stem Cell Biology

Stem cells raise enormous hope and expectations for regenerative medicine. Since decades hematopoietic stem cell transplantation has become routine treatment for many blood disorders and cancer and is a prime example for successfully applied regenerative medicine. However, many fundamental questions must be addressed for improved therapeutic options in the future.

We focus our research on basic mechanisms that control stem cell fate decisions (self-renewal vs. differentiation, lineage choice, quiescence vs. proliferation). These fate decisions need to be strictly balanced for normal tissue regeneration and for emergency situations, and are dysregulated in diseases (e.g. cancer). We utilize various organ stem cell systems (hematopoietic cells, mammary gland, colon) from mice and humans to unravel molecular and functional clues how these decisions are integrated in normal stem cell biology and how malignant stem cells can be targeted for innovative disease treatment.

Our Mission

We need a detailed knowledge about normal stem cell behavior to create innovative therapies for dysregulated stem-cell driven diseases.

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portrait Michael Rieger

Prof. Dr. Michael Rieger

Curriculum Vitae

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